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Melvin E. Carnahan Professor of Pediatrics; Unit Leader Pathobiology; Director Division of Pediatric Gastroenterology and Nutrition

• Gastroenterology and Nutrition
• Pathobiology
• Phillip I. Tarr Research Lab

Education

• A.B., Brown University, 1975
• M.D., Yale University, 1980

Training

• Pediatric Residency, University of Washington, Seattle, Wa., 1980-83
• Assistant Chief Resident, Department of Pediatrics, University of Washington School of Medicine/Children's Orthopedic Hospital and Medical Center, Seattle, Wa., 1982-83
• Infectious Diseases Fellowship, University of Washington, Seattle, Wa., 1983-87
• Senior Fellow, Division of Infectious Diseases, Department of Medicine, University of Washington School of Medicine, Seattle, Wa., 1983-86
• Research Associate, Seattle Biomedical Research Institute, Seattle, Wa., 1986-87
• Gastroenterology Fellowship, University of Washington, Seattle, Wa., 1988-89

Licensure and Board Certification

• Washington License, 1981
• Missouri License, 2003
• American Board of Pediatrics, 1984
• Pediatric Gastroenterology, 1993
• Pediatric Gastroenterology (Re-certification), 1999

Selected Publications

1. Bielaszewska, M., Zhang, W., Tarr PI, P. I., Sonntag, A. K. & Karch, H.: Molecular profiling and phenotype analysis of Escherichia coli O26:H11 and O26:NM: secular and geographic consistency of enterohemorrhagic and enteropathogenic isolates. J Clin Microbiol 43 4225-8 (2005).

2. Ake, J. A. et al.: Relative nephroprotection during Escherichia coli O157:H7 infections: association with intravenous volume expansion. Pediatrics 115 e673-80 (2005).

3. John, M. et al.: Use of in vivo-induced antigen technology for identification of Escherichia coli O157:H7 proteins expressed during human infection. Infect Immun 73, 2665-79 (2005).

4. Tarr PI, Gordon, C. A. & Chandler, W. L.: Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome. Lancet 365, 1073-86 (2005).

5. Johnson, J. R. et al. : The IrgA homologue adhesin Iha is an Escherichia coli virulence factor in murine urinary tract infection. J Infect Dis 188, 719-29 (2005).

6. Jelacic, J. K. et al: Shiga toxin-producing Escherichia coli in Montana: bacterial genotypes and clinical profiles. J Infect Dis 188, 719-29 (2003).

7. Johnson, J. R., Lockman, H. A., Owens, K., Jelacic, S. & Tarr PI: High-frequency secondary mutations after suicide-driven allelic exchange mutagenesis in extraintestinal pathogenic Escherichia coli. J Bacteriol 185, 5301-5 (2003).

8. Shaikh, N. & Tarr PI: Escherichia coli O157:H7 Shiga toxin-encoding bacteriophages: integrations, excisions, truncations, and evolutionary implications. J Bacteriol 185, 3596-605 (2003).