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Publications

Selected Publications

1. Vohra BP, Planer W, Armon J, Fu M, Jain S, Heuckeroth RO.: Reduced endothelin converting enzyme-1 and endothelin-3 mRNA in the developing bowel of male mice may increase expressivity and penetrance of Hirschsprung disease-like distal intestinal aganglionosis. Dev Dyn. 2007 Jan;236(1):106-17. [ pubmed ]

2. Fu M, Vohra BP, Wind D, Heuckeroth RO.: BMP signaling regulates murine enteric nervous system precursor migration, neurite fasciculation, and patterning via altered Ncam1 polysialic acid addition. Dev Biol. 2006 Nov 1;299(1):137-50 [ pubmed ]

3. Vohra BP, Tsuji K, Nagashimada M, Uesaka T, Wind D, Fu M, Armon J, Enomoto H, Heuckeroth RO.: Differential gene expression and functional analysis implicate novel mechanisms in enteric nervous system precursor migration and neuritogenesis. Dev Biol. 2006 Oct 1;298(1):259-71 [ pubmed ]

4. Wang H, Vohra BP, Zhang Y, Heuckeroth RO.: Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice. Hepatology. 2005 Nov;42(5):1099-108. [ pubmed ]

5. Srinivasan S, Anitha M, Mwangi S, Heuckeroth RO.: Enteric neuroblasts require the phosphatidylinositol 3-kinase/Akt/Forkhead pathway for GDNF-stimulated survival. Mol Cell Neurosci. 2005 May;29(1):107-19 [ pubmed ]

6. Gianino S, Grider JR, Cresswell J, Enomoto H, Heuckeroth RO.: GDNF availability determines enteric neuron number by controlling precursor proliferation. Development. 2003 May;130(10):2187-98. [ pubmed ]

7. Heuckeroth RO, Enomoto H, Grider JR, Golden JP, Hanke JA, Jackman A, Molliver DC, Bardgett ME, Snider WD, Johnson EM Jr, Milbrandt J.: Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons. Neuron. 1999 Feb;22(2):253-63. [ pubmed ]

Selected Reviews

1. Heuckeroth R, Pachnis, V : Getting to the guts of enteric nervous system development. Development. 2006 Jun;133(12):2287-90. [ pubmed ]

2. Heuckeroth RO: Finding your way to the end: a tale of GDNF and endothelin-3. Neuron. 2003 Dec 4;40(5):871-3 [ pubmed ]

3. Heuckeroth RO: Autonomic and enteric nervous system: apoptosis, trophic factors, and the mechanisms that control neuron number and function New Encyclopedia of Neuroscience. 2007, in press.