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Recent fellow grant support (past 3 years) - Jessica Boyd, M.D., T32 Training Grant, Developmental Cardiology and Pulmonary Medicine
- Audrey Wells, M.D., Pediatric Scientist Development Award
- Katherine Rivera-Spoljaric, M.D., K30 Award, Mentored Training Program in Clinical Investigation
- Avraham Beigelman, M.D., K30 Award, Mentored Training Program in Clinical Investigation
Selected recent fellow publications (past 3 years) - Boyd JH, Macklin EA, Strunk RC, DeBaun MR: Asthma is associated with increased mortality in individuals with sickle cell anemia. Haematologica 2007:92:1115-8.
- Boyd JH, DeBaun MR, Morgan WJ, Mao J, Strunk RC: Lower airway obstruction is associated with increased morbidity in children with sickle cell disease. Pediatr Pulmonol. 2009;44:290-6
- Elizur A, Adair-Kirk TL, Kelley DG, Griffin GL, deMello DE, Senior RM: Tumor necrosis factor-alpha from macrophages enhances LPS-induced clara cell expression of keratinocyte-derived chemokine. Am J Respir Cell Mol Biol 2008;38:8-15.
- Elizur A, Faro A, Huddleston CB, Gandhi SK, White D, Kuklinski CA, Sweet SC: Lung transplantation in infants and toddlers from 1990 to 2004 at St. Louis Children's Hospital. Am J Transplant. 2009;9:719-26.
- Elizur A, Adair-Kirk TL, Kelley DG, Griffin GL, deMello DE, Senior RM: Clara cells impact the pulmonary innate immune response to LPS. Am J Physiol Lung Cell Mol Physiol 2007;293:L383-92.
- Elizur A, Bacharier LB, Strunk RC: Pediatric asthma admissions: chronic severity and acute exacerbations. J Asthma 2007;44:285-9.
- Elizur A, Cannon CL, Ferkol TW: Airway inflammation in cystic fibrosis. Chest 2008;133:489-95.
- Elizur A, Kannai Y, Pollack N, Katz Y: Maternal positive skin prick test results and asthma prediction after early childhood wheezing. Ann Immunol 2007;98:540-45.
- Elizur A, Orscheln RC, Ferkol TW, Atkinson JJ, Dunne WM, Buller RS, Armstrong JR, Mardis ER: Panton-Valentine Leukocidin-positive methicillin-resistant Staphylococcus aureus lung infections in patients with cystic fibrosis. Chest 2007;131:1718-25.
- Elizur A, Orscheln RC, Ferkol TW, Dunne WM, Storch GA, Cannon CL: Transmission of Panton-Valentine Leukocidin-positive Staphylococcus aureus between cystic fibrosis patients. J Pediatr 2007;151:90-92.
- Elizur A, Sweet SC, Huddleston CB, Gandhi SK, Boslaugh SE, Kulinski CA, Faro A: Pre-transplant mechanical ventilation increases short term morbidity and mortality in pediatric patient with cystic fibrosis. J Heart Lung Transplant 2007;26:127-31.
- Hindi KM, Ditto AJ, Panzner MJ, Medvetz DA, Han DS, Hovis CE, Hilliard JK, Taylor JB, Yun YH, Cannon CL, Youngs WJ: The antimicrobial efficacy of sustained release silver-carbene complex-loaded L-tyrosine polyphosphate nanoparticles: characterization, in vitro and in vivo studies. Biomaterials. 2009;30:3771-9.
- Jennings JE, Ramkumar T, Mao J, Boyd J, Castro M, Field JJ, Strunk RC, DeBaun MR: Elevated urinary leukotriene E4 levels are associated with hospitalization for pain in children with sickle cell disease. Am J Hematol. 2008;83:640-3.
- Khan SH, Park SS, Sirajuddin IA, Grayson MH: Respiratory virus and asthma: The role of immunoglobulin E. Clin Ther 2008;30:1017-24.
- Lie H, Ferkol T: Primary ciliary dyskinesia: recent advances in pathogenesis, diagnosis and treatment. Drugs. 2007;67:1883-92.
- Phillips KL, An P, Boyd JH, Strunk RC, Casella JF, Barton BA, DeBaun MR: Major gene effect and additive familial pattern of inheritance of asthma exist among families of probands with sickle cell anemia and asthma. Am J Hum Biol 2008:20:149-53.
- Rivera-Spoljaric K, Chinchilli VM, Camera LJ, Zeiger RS, Paul IM, Phillips BR, Taussig LM, Strunk RC, Bacharier LB: Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezing. J Pediatr. 2009;154:877-81.
- Silver E, Yin-Declue H, Schechtman KB, Grayson MH, Bacharier LB, Castro M: Lower levels of plasmacytoid dendritic cells in peripheral blood are associated with a diagnosis of asthma 6 years after severe respiratory syncytial virus bronchiolitis. Pediatr Allergy Immunol. 2009. In press.
- Shornick LP, Wells AG, Zhang Y, Patel AC, Huang G, Takami K, Sosa M, Shukla N, Agapov E, Holtzman MJ: Host tissue versus immune cell stat1 function for innate defense against respiratory viral infection. J Immunol 2008;180:3319-28.
- Spivey JF, Singleton D, Sweet S, Storch GA, Hayashi RJ, Huddleston CB, Danziger-Isakov LA: Safety and efficacy of prolonged cytomegalovirus prophylaxis with intravenous ganciclovir in pediatric and young adult lung transplant recipients. Pediatr Transplant 2007;11:312-8.
- Spivey JF, Uong EC, Strunk R, Boslaugh SE, DeBaun MR: Low daytime pulse oximetry reading is associated with nocturnal desaturation and obstructive sleep apnea in children with sickle cell anemia. Pediatr Blood Cancer 2008;50:359-62.
- Strunk RC, Brown MS, Boyd JH, Bates P, Field JJ, DeBaun MR: Methacholine challenge in children with sickle cell disease: a case series. Pediatr Pulmonol. 2008;43:924-9.
Recent fellow grant support (past 3 years) - Jessica Boyd, M.D., T32 Training Grant, Developmental Cardiology and Pulmonary Medicine
- Audrey Wells, M.D., Pediatric Scientist Development Award
- Katherine Rivera-Spoljaric, M.D., K30 Award, Mentored Training Program in Clinical Investigation
- Avraham Beigelman, M.D., K30 Award, Mentored Training Program in Clinical Investigation
Selected recent fellow publications (past 3 years) - Boyd JH, Macklin EA, Strunk RC, DeBaun MR: Asthma is associated with increased mortality in individuals with sickle cell anemia. Haematologica 2007:92:1115-8.
- Boyd JH, DeBaun MR, Morgan WJ, Mao J, Strunk RC: Lower airway obstruction is associated with increased morbidity in children with sickle cell disease. Pediatr Pulmonol. 2009;44:290-6
- Elizur A, Adair-Kirk TL, Kelley DG, Griffin GL, deMello DE, Senior RM: Tumor necrosis factor-alpha from macrophages enhances LPS-induced clara cell expression of keratinocyte-derived chemokine. Am J Respir Cell Mol Biol 2008;38:8-15.
- Elizur A, Faro A, Huddleston CB, Gandhi SK, White D, Kuklinski CA, Sweet SC: Lung transplantation in infants and toddlers from 1990 to 2004 at St. Louis Children's Hospital. Am J Transplant. 2009;9:719-26.
- Elizur A, Adair-Kirk TL, Kelley DG, Griffin GL, deMello DE, Senior RM: Clara cells impact the pulmonary innate immune response to LPS. Am J Physiol Lung Cell Mol Physiol 2007;293:L383-92.
- Elizur A, Bacharier LB, Strunk RC: Pediatric asthma admissions: chronic severity and acute exacerbations. J Asthma 2007;44:285-9.
- Elizur A, Cannon CL, Ferkol TW: Airway inflammation in cystic fibrosis. Chest 2008;133:489-95.
- Elizur A, Kannai Y, Pollack N, Katz Y: Maternal positive skin prick test results and asthma prediction after early childhood wheezing. Ann Immunol 2007;98:540-45.
- Elizur A, Orscheln RC, Ferkol TW, Atkinson JJ, Dunne WM, Buller RS, Armstrong JR, Mardis ER: Panton-Valentine Leukocidin-positive methicillin-resistant Staphylococcus aureus lung infections in patients with cystic fibrosis. Chest 2007;131:1718-25.
- Elizur A, Orscheln RC, Ferkol TW, Dunne WM, Storch GA, Cannon CL: Transmission of Panton-Valentine Leukocidin-positive Staphylococcus aureus between cystic fibrosis patients. J Pediatr 2007;151:90-92.
- Elizur A, Sweet SC, Huddleston CB, Gandhi SK, Boslaugh SE, Kulinski CA, Faro A: Pre-transplant mechanical ventilation increases short term morbidity and mortality in pediatric patient with cystic fibrosis. J Heart Lung Transplant 2007;26:127-31.
- Hindi KM, Ditto AJ, Panzner MJ, Medvetz DA, Han DS, Hovis CE, Hilliard JK, Taylor JB, Yun YH, Cannon CL, Youngs WJ: The antimicrobial efficacy of sustained release silver-carbene complex-loaded L-tyrosine polyphosphate nanoparticles: characterization, in vitro and in vivo studies. Biomaterials. 2009;30:3771-9.
- Jennings JE, Ramkumar T, Mao J, Boyd J, Castro M, Field JJ, Strunk RC, DeBaun MR: Elevated urinary leukotriene E4 levels are associated with hospitalization for pain in children with sickle cell disease. Am J Hematol. 2008;83:640-3.
- Khan SH, Park SS, Sirajuddin IA, Grayson MH: Respiratory virus and asthma: The role of immunoglobulin E. Clin Ther 2008;30:1017-24.
- Lie H, Ferkol T: Primary ciliary dyskinesia: recent advances in pathogenesis, diagnosis and treatment. Drugs. 2007;67:1883-92.
- Phillips KL, An P, Boyd JH, Strunk RC, Casella JF, Barton BA, DeBaun MR: Major gene effect and additive familial pattern of inheritance of asthma exist among families of probands with sickle cell anemia and asthma. Am J Hum Biol 2008:20:149-53.
- Rivera-Spoljaric K, Chinchilli VM, Camera LJ, Zeiger RS, Paul IM, Phillips BR, Taussig LM, Strunk RC, Bacharier LB: Signs and symptoms that precede wheezing in children with a pattern of moderate-to-severe intermittent wheezing. J Pediatr. 2009;154:877-81.
- Silver E, Yin-Declue H, Schechtman KB, Grayson MH, Bacharier LB, Castro M: Lower levels of plasmacytoid dendritic cells in peripheral blood are associated with a diagnosis of asthma 6 years after severe respiratory syncytial virus bronchiolitis. Pediatr Allergy Immunol. 2009. In press.
- Shornick LP, Wells AG, Zhang Y, Patel AC, Huang G, Takami K, Sosa M, Shukla N, Agapov E, Holtzman MJ: Host tissue versus immune cell stat1 function for innate defense against respiratory viral infection. J Immunol 2008;180:3319-28.
- Spivey JF, Singleton D, Sweet S, Storch GA, Hayashi RJ, Huddleston CB, Danziger-Isakov LA: Safety and efficacy of prolonged cytomegalovirus prophylaxis with intravenous ganciclovir in pediatric and young adult lung transplant recipients. Pediatr Transplant 2007;11:312-8.
- Spivey JF, Uong EC, Strunk R, Boslaugh SE, DeBaun MR: Low daytime pulse oximetry reading is associated with nocturnal desaturation and obstructive sleep apnea in children with sickle cell anemia. Pediatr Blood Cancer 2008;50:359-62.
- Strunk RC, Brown MS, Boyd JH, Bates P, Field JJ, DeBaun MR: Methacholine challenge in children with sickle cell disease: a case series. Pediatr Pulmonol. 2008;43:924-9.
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