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Faculty Bio

Grady, R. Mark, M.D.

Associate Professor of Pediatrics

Cardiology
Education
  • B.A. - Princeton University, Princeton, NJ
  • M.D./M.A. - Washington University School of Medicine, St. Louis, Mo.
Training
  • Residency, Pediatrics - St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, Mo.
  • Fellowship, Pediatric Cardiology - St. Louis Children's Hospital, St. Louis, Mo.
Licensure and Board Certification
  • American Board of Pediatrics
  • American Board of Pediatrics, Sub-Board of Pediatric Cardiology
Selected Publications

 

  1. Grady RM, Teng H, Nichol MC, CunninghamJC, Wilkinson RS, Sanes JR. Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy. Cell, 1997; 90:729-738.

  2. Grady RM, Merlie JP, Sanes JR: Subtle neuromuscular defects in utrophin-deficient mice. J. Cell Biol. 1997; 136:871-882.

  3. Grady RM, Grange RW, Lau KS, Maimone MM, Nichol MC, Stull JT, Sanes JR: Role for a-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies. Nature Cell Biol. 1999; 1:215-220.

  4. Grady RM, Zhou H, Cunningham JM, and Sanes JR: Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin glycoprotein complex. Neuron 2000; 25:279-293.

  5. Grady RM, Wozniak DF, Ohlemiller KK, Sanes JR: Cerebellar synaptic defects and abnormal motor behavior in mice lacking a- and B-dystrobrevin. J Neurosci 2006; 26:2841-2851.

  6. Grady RM, Starr DA, Ackerman GL, Sanes JR, Han M: Syne proteins anchor muscle nuclei at the neuromuscular junction. Invited commentary: Ruegg MA, 102:5643-5644, 2005. Proc Natl Acad Sci USA 2005; 102:4359-4364.

  7. Levi S, Grady RM, Henry MD, Campbell KP, Sanes JR, Craig AM: Dystroglycan is selectively associated with inhibitory GABAergic synapses but is dispensible for their differentiation. J Neuroscience 2002; 22:4274-4285.

  8. Grady RM, Akaaboune M, Cohen AL, Maimone MM, Lichtman JW, Sanes JR: Tyrosine-phosphorylated and nonphosphorylated isoforms of a-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions. J Cell Biol. 2003; 160:741-752.

  9. Grady RM, Starr DA, Ackerman GL, Sanes JR, Han M. Syne proteins anchor muscle nuclei at the neuromuscular junction. Proc Natl Acad Sci USA, 102:4359-4364, 2005. Invited commentary: Ruegg MA, 102:5643-5644, 2005.

  10. Grady RM, Wozniak DF, Ohlemiller KK, Sanes JR. Cerebellar synaptic defects and abnormal motor behavior in mice lacking ?- and ?-dystrobrevin. J Neurosci, 26:2841-2851, 2006.

  11. Gandhi SK, Grady RM, Huddleston CB, Balzer DT, Canter CE. Beyond Berlin: Heart transplantation in the "untransplantable". J Thorac Cardiovasc Surg, 136:529-531, 2008.

  12. Grady RM, Gandhi S, Sweet SC, Mao J, Huddleston CB. Dismal lung transplantation in children with tetralogy of Fallot with pulmonary atresia compared to Eisenmenger syndrome or pulmonary vein stenosis. J Heart Lung Transplant, 28:1221-5, 2009.

 
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