Assistant Professor of Pediatrics

• Cardiology
• R. Mark Grady Research Lab

Education

• B.A. - Princeton University, Princeton, NJ
• M.D./M.A. - Washington University School of Medicine, St. Louis, Mo.

Training

• Residency, Pediatrics - St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, Mo.
• Fellowship, Pediatric Cardiology - St. Louis Children's Hospital, St. Louis, Mo.

Licensure and Board Certification

• American Board of Pediatrics
• American Board of Pediatrics, Sub-Board of Pediatric Cardiology

Selected Publications

1. Grady RM, Teng H, Nichol MC, CunninghamJC, Wilkinson RS, Sanes JR: Skeletal and cardiac myopathies in mice lacking utrophin and dystrophin: a model for Duchenne muscular dystrophy. Cell 1997; 90:729-738.

2. Grady RM, Merlie JP, Sanes JR: Subtle neuromuscular defects in utrophin-deficient mice. J. Cell Biol. 1997; 136:871-882.

3. Grady RM, Grange RW, Lau KS, Maimone MM, Nichol MC, Stull JT, Sanes JR: Role for a-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies. Nature Cell Biol. 1999; 1:215-220.

4. Grady RM, Zhou H, Cunningham JM, and Sanes JR: Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin glycoprotein complex. Neuron 2000; 25:279-293.

5. Grady RM, Wozniak DF, Ohlemiller KK, Sanes JR: Cerebellar synaptic defects and abnormal motor behavior in mice lacking a- and B-dystrobrevin. J Neurosci 2006; 26:2841-2851.

6. Grady RM, Starr DA, Ackerman GL, Sanes JR, Han M.: Syne proteins anchor muscle nuclei at the neuromuscular junction. Invited commentary: Ruegg MA, 102:5643-5644, 2005. Proc Natl Acad Sci USA 2005; 102:4359-4364.

7. Levi S, Grady RM, Henry M.D., Campbell KP, Sanes JR, Craig AM: Dystroglycan is selectively associated with inhibitory GABAergic synapses but is dispensible for their differentiation. J Neuroscience 2002; 22:4274-4285.

8. Grady RM, Akaaboune M, Cohen AL, Maimone MM, Lichtman JW, Sanes JR: Tyrosine-phosphorylated and nonphosphorylated isoforms of a-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions. J Cell Biol. 2003; 160:741-752.