Jonathan D. Gitlin, M.D. [ contact information ]
Helene B. Roberson Professor of Pediatrics and Professor of Genetics, Scientific Director, Children's Discovery Institute;
Director Division of Genetics and Genomic Medicine;
Unit Leader Developmental Biology and Genetics
Jonathan D. Gitlin is the Helene B. Roberson Professor of Pediatrics
and Professor of Genetics at the Washington University School of
Medicine and Scientific Director of the Children’s Discovery Institute, a
joint research venture between Washington University and St. Louis Children’s
Hospital. Dr. Gitlin received his medical degree from the University of
Pittsburgh, completed his pediatric residency and fellowship at the
Children's Hospital Medical Center in Boston and was on the faculty at
the Harvard Medical School before coming to Washington University in 1986.
He is board certified in Pediatrics and teaches and cares for patients at
St. Louis Children's Hospital where he is currently Chief of the Division
of Genetics & Genomic Medicine. In 1999 he was designated Clinical Teacher
of the Year at the Washington University School of Medicine. Dr. Gitlin
is a member of the American Society for Clinical Investigation, the
Association of American Physicians, the Society for Pediatric Research
and the American Pediatric Society. His research has focused on the
inorganic chemistry of living organisms and currently utilizes zebrafish as
an experimental system to explore the role of genetics and nutrition in
early human development. In recognition of this scholarship he has received
numerous awards, including the E. Mead Johnson Award for Excellence in
Research from the Society for Pediatric Research, the Samuel Rosenthal
Foundation Award for Excellence in Academic Pediatrics, the Chancellor’s
Hartwell Prize for Innovative Research from Washington University and a
MERIT Award for prestigious research from the National Institutes of Health.
Selected Publications
Schlief ML, Craig AM, Gitlin JD:
NMDA receptor activation mediates copper homeostasis in hippocampal neurons.
J Neurosci
2005; 25:239-246.
Caruano-Yzermans AL, Bartnikas TB, Gitlin JD:
Mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase.
J Biol Chem
2006; 281:13581-13587.
Mendelsohn BA, Yin C, Johnson SL, Wilm T, Solnica-Krezel L, Gitlin JD:
Atp7a determines a hierarchy of copper metabolism essential for notochord development.
Cell Metabolism
2006; 4:155-162.
Samuels TK, Gitlin JD:
Copper and nitric oxide meet in the plasma.
Nature Chem Biol
2006; 2:452-453.
Schlief ML, West T, Craig AM, Holtzman DM, Gitlin JD:
Role of the Menkes copper transporting atpase in NMDA receptor-mediated neuronal toxicity.
Proc Natl Acad Sci USA
2006; 103:In Press.
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