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Faculty Bio

Aaron Hamvas, M.D.

James P. Keating, M.D. Professor of Pediatrics
Director of Clinical Affairs for Newborn Medicine
 
 
Areas of Clinical Interest/Research
Genetic disorders of surfactant metabolism; genetic contribution to lung disease in newborns; influence of the intestinal microbiome on newborn respiratory disease.
Education
  • BS, Rensselaer Polytechnic Institute, Troy, NY, 1977
  • MD, Washington University School of Medicine, St. Louis, MO, 1981
Training
  • Residency, St. Louis Children's Hospital, St. Louis, Missouri, 1981 - 1984
  • Fellow in Newborn Medicine, St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, Missouri, 1987 - 1990
Licensure and Board Certification
  • Missouri, 1983
  • American Board of Pediatrics, 1989
  • Sub-Board of Neonatal-Perinatal Medicine, 1991, recertified 1998, 2006
Memberships
  • The Society for Pediatric Research
  • Midwest Society for Pediatric Research
  • American Pediatric Society
  • American Thoracic Society
  • Pediatric Program Committee 

 

Selected Publications
  • Hamvas A, Wegner DJ, Carlson CS, Bergmann KR, Trusgnich MA, Fulton L, Kasai Y, An P, Mardis ER, Wilson RK, Cole FS. Comprehensive genetic variant discovery in the surfactant protein B gene. Pediatr Res 2007; 62: 170–175. PMCID: PMC2765713

  • McBee AD, Wegner DJ, Carlson CS, Wambach JA, Yang P, Heins HB, Saugstad OD, Trusgnich MA, Watkins-Torry J, Nogee LM, Henderson H, Cole FS, Hamvas A. Recombination as a mechanism for sporadic mutation in the surfactant protein-C gene. Pediatr Pulmonol 2008; 43:443-450. PMCID: PMC2765708

  • Garmany TH, Wambach JA, Heins HB, Watkins-Torry J, Wegner DJ, Bennet K, An P, Land G, Saugstad OD, Henderson H, Nogee LM, Cole FS, Hamvas A. Population and Disease-based Prevalence of the Common Mutations Associated with Surfactant Deficiency. Pediatr Res 2008; 63:645-649. PMCID: PMC2765719

  • Hamvas A, Heins HB, Guttentag SH, Wegner DJ, Trusgnich MA, Bennet KW, Yang P, Carlson CS, An P, Cole FS. Developmental and Genetic Regulation of Human Surfactant Protein-B In Vivo. Neonatology 2009; 95:117-124. PMCID: PMC2765709

  • Hamvas A, Nogee LM, Wegner DJ, DePass K, Christodoulou J, Bennetts B, McQuade LR, Gray PH, Deterding RR, Carroll TR, Kammesheidt A, Kasch LM, Kulkarni S, Cole FS. Inherited surfactant deficiency due to uniparental disomy of rare mutations in the surfactant protein-B and ATP binding cassette, subfamily A, member 3 genes. J Pediatr 2009; 155:854-859.e1. PMCID: PMC2794197

  • Wambach JA, Yang P, Wegner DJ, An P, Hackett BP, Cole FS, Hamvas A. Surfactant protein-C promoter variants associated with neonatal respiratory distress syndrome reduce transcription. Pediatr Res 2010; 68:216-220. PMID: 20539253. PMCID: PMC2921462

  • Anadkat JS, Kuzniewicz MW, Chaudhari B, Cole FS, Hamvas A. Race and sex provide differential risks for respiratory distress syndrome in late preterm and term infants. J Perinatol 2012 Jan 5. doi: 10.1038/jp.2011.191. PMID: 22222548

  • Hamvas A. Current technology in the diagnosis of developmentally related lung disorders. Neonatology 2012; 101:353-359. Wambach J, Wegner D, DePass K, Heins H, Druley T, Mitra R, An P, Zhang Q, Nogee LM, Cole FS, Hamvas A. Single ABCA3 Mutations and Risk for Neonatal Respiratory Distress Syndrome. Pediatr 2012; in press.

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