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Shalini Shenoy, M.D.
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Associate Professor of Pediatrics
Attending Physician in Hematology/Oncology and General Pediatrics
Director, Pediatric Bone Marrow Transplant Program
Patient Oriented Research
Hematology and Oncology
Dr. Shenoy's research interests are focused on transplantation biology and the immunologic mechanisms of graft rejection, and graft versus host disease (GVHD), and immune reconstitution following bone marrow transplantation (BMT). Another area of investigation pursued by Dr. Shenoy is the mechanism of T cell deletion and the role of Fas-fas ligand in GVHD and autoimmune disease.
Dr. Shenoy's clinical research is focused on developing safe and effective reduced intensity conditioning regimen in stem cell transplantation, especially as it relates to metabolic and non-malignant disorders, and she has published several articles on this subject. She is the Prinicipal Investigator on a national trial of unrelated donor transplantation for severe sickle cell disease termed the SCURT Trial (Bone Marrow Transplant Clinical Trials Network 0601). Other clinical trials for non-malignant disorders are also underway.
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Shalini Shenoy, M.D.
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Associate Professor of Pediatrics
Attending Physician in Hematology/Oncology and General Pediatrics
Director, Pediatric Bone Marrow Transplant Program
Patient Oriented Research
Hematology and Oncology
Dr. Shenoy's research interests are focused on transplantation biology and the immunologic mechanisms of graft rejection, and graft versus host disease (GVHD), and immune reconstitution following bone marrow transplantation (BMT). Another area of investigation pursued by Dr. Shenoy is the mechanism of T cell deletion and the role of Fas-fas ligand in GVHD and autoimmune disease.
Dr. Shenoy's clinical research is focused on developing safe and effective reduced intensity conditioning regimen in stem cell transplantation, especially as it relates to metabolic and non-malignant disorders, and she has published several articles on this subject. She is the Prinicipal Investigator on a national trial of unrelated donor transplantation for severe sickle cell disease termed the SCURT Trial (Bone Marrow Transplant Clinical Trials Network 0601). Other clinical trials for non-malignant disorders are also underway.
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- M.B.B.S., Kasturba Medical College, Mysore University, 1981
- Doctor of Medicine in Pediatrics, Kasturba Medical College, Manipal, Mangalore University, 1985
- M.B.B.S., Kasturba Medical College, Mysore University, 1981
- Doctor of Medicine in Pediatrics, Kasturba Medical College, Manipal, Mangalore University, 1985
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- Residency in General Pediatrics, LSUMC and Charity Hospital, New Orleans,
1989-1991
- Fellow in Pediatric Hematology/Oncology, Washington University School of Medicine, 1992
- Fellow in Pediatric Hematology/Oncology, Washington University School of Medicine, 1992-1995
- Residency in General Pediatrics, LSUMC and Charity Hospital, New Orleans,
1989-1991
- Fellow in Pediatric Hematology/Oncology, Washington University School of Medicine, 1992
- Fellow in Pediatric Hematology/Oncology, Washington University School of Medicine, 1992-1995
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- Missouri License, 1994
- Pediatric Board Certified, 1991; recertified 1999
- Pediatric Hematology and Oncology, 1996; recertified 2002
- Missouri License, 1994
- Pediatric Board Certified, 1991; recertified 1999
- Pediatric Hematology and Oncology, 1996; recertified 2002
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- National Institutes of Health, Mentored Clinical Scientist Development Award,
1997-2002
- American Cancer Society, Institutional Research Grant, 1997-1998
- ASHI Scholar, 2001
- National Institutes of Health, Mentored Clinical Scientist Development Award,
1997-2002
- American Cancer Society, Institutional Research Grant, 1997-1998
- ASHI Scholar, 2001
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- Shenoy S, Grossman W, DiPersio J, Yu L, Wilson D, Barnes Y, Mohanakumar T, Rao A and Hayashi R. A novel reduced intensity stem cell transplant regimen for non-malignant disorders. Bone Marrow Transplant 2005; 35 (4): 345-52.
- Grewal S, Wynn R, Abdenur JE, Burton B, Gharib M, Haase C, Hayashi RJ, Shenoy S, Sillence D, Dudek T, Royen-Kerkhof A, Brinkman J, Wraith J, Woodard P, Young G, Wulffraat N, Whitley C, and Peters C. Safety and Efficacy of Enzyme Replacement Therapy in Combination with Hematopoietic Stem Cell Transplantation in Hurler syndrome. Genetics in Medicine 2005; 7 (2): 143.
- Oza A, Hallemeier C, Goodnough L, Khoury H, Shenoy S, Devine S, Augustin K, Vij R, Trinkaus K, DiPersio JF, Adkins D. Prophylactic Granulocyte Transfusions Given Following Allogeneic Peripheral Blood Stem Cell Transplantation Result In a Modest Reduction Of Febrile Days and Intravenous Antibiotic Usage. Transfusion 2006; 46 (1): 14-23.
- Rao A, Kamani N, Filipovich A, Molleran Lee S, Davies SM, Dalal J and Shenoy S. Successful Bone Marrow Transplantation for IPEX Syndrome Following Reduced Intensity Conditioning. Blood 2007; 109: 383-5.
- Hansen M, Davies SM, Filipovich AH, Mehta P, Bleesing J, Hayashi RJ, Barnes YJ, and Shenoy S. Allogeneic Hematopoietic Cell Transplantation (HCT) in Hurler Syndrome using a Reduced Intensity Preparative Regimen. Bone Marrow Transplant 2008; 41: 349-53.
- Rao A, Kelly M, Musselman M, Ramadas J, Grossman W and Shenoy S. Safety, efficacy and immune reconstitution after anti-CD20 monoclonal antibody for pediatric autoimmune cytopenias. Pediatr Blood Cancer 2008; 50(4): 822-5. E-Pub June 14, 2007.
- Fong T, Trinkaus K, Adkins D, Vij R, Devine SM, Tomasson M, Goodnough L, Lopez S, Graubert T, Shenoy S, DiPersio J, Khoury HJ. A randomized double blind trial ofhydroxychloroquine for the prevention of chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation. Biology of Blood and Marrow Transplant 2007; 13 (10): 1201-6.
- Druley TE, Hayashi RJ, Mansur DB, Zhang J, Barnes YJ, Trinkaus K, Witty S, Thomas, T, Klein EE, DiPersio JF, Adkins D and Shenoy S. Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients with Hematologic Malignancies Following Single Fraction Total Body Irradiation. Bone Marrow Transplant. In Press.
- Bhatla D, Davies SM, Shenoy S, Harris RE, Smolarek TA, Bleesing J, Hansen M, Jodele S, Jordan M, Filipovich AH, Mehta PA. Successful transplantation of Shwachman Diamond Syndrome using a reduced intensity conditioning regimen. Bone Marrow Transplant. May 26, 2008. 42(3):159-65.
- Shenoy S, Grossman W, DiPersio J, Yu L, Wilson D, Barnes Y, Mohanakumar T, Rao A and Hayashi R. A novel reduced intensity stem cell transplant regimen for non-malignant disorders. Bone Marrow Transplant 2005; 35 (4): 345-52.
- Grewal S, Wynn R, Abdenur JE, Burton B, Gharib M, Haase C, Hayashi RJ, Shenoy S, Sillence D, Dudek T, Royen-Kerkhof A, Brinkman J, Wraith J, Woodard P, Young G, Wulffraat N, Whitley C, and Peters C. Safety and Efficacy of Enzyme Replacement Therapy in Combination with Hematopoietic Stem Cell Transplantation in Hurler syndrome. Genetics in Medicine 2005; 7 (2): 143.
- Oza A, Hallemeier C, Goodnough L, Khoury H, Shenoy S, Devine S, Augustin K, Vij R, Trinkaus K, DiPersio JF, Adkins D. Prophylactic Granulocyte Transfusions Given Following Allogeneic Peripheral Blood Stem Cell Transplantation Result In a Modest Reduction Of Febrile Days and Intravenous Antibiotic Usage. Transfusion 2006; 46 (1): 14-23.
- Rao A, Kamani N, Filipovich A, Molleran Lee S, Davies SM, Dalal J and Shenoy S. Successful Bone Marrow Transplantation for IPEX Syndrome Following Reduced Intensity Conditioning. Blood 2007; 109: 383-5.
- Hansen M, Davies SM, Filipovich AH, Mehta P, Bleesing J, Hayashi RJ, Barnes YJ, and Shenoy S. Allogeneic Hematopoietic Cell Transplantation (HCT) in Hurler Syndrome using a Reduced Intensity Preparative Regimen. Bone Marrow Transplant 2008; 41: 349-53.
- Rao A, Kelly M, Musselman M, Ramadas J, Grossman W and Shenoy S. Safety, efficacy and immune reconstitution after anti-CD20 monoclonal antibody for pediatric autoimmune cytopenias. Pediatr Blood Cancer 2008; 50(4): 822-5. E-Pub June 14, 2007.
- Fong T, Trinkaus K, Adkins D, Vij R, Devine SM, Tomasson M, Goodnough L, Lopez S, Graubert T, Shenoy S, DiPersio J, Khoury HJ. A randomized double blind trial ofhydroxychloroquine for the prevention of chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation. Biology of Blood and Marrow Transplant 2007; 13 (10): 1201-6.
- Druley TE, Hayashi RJ, Mansur DB, Zhang J, Barnes YJ, Trinkaus K, Witty S, Thomas, T, Klein EE, DiPersio JF, Adkins D and Shenoy S. Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients with Hematologic Malignancies Following Single Fraction Total Body Irradiation. Bone Marrow Transplant. In Press.
- Bhatla D, Davies SM, Shenoy S, Harris RE, Smolarek TA, Bleesing J, Hansen M, Jodele S, Jordan M, Filipovich AH, Mehta PA. Successful transplantation of Shwachman Diamond Syndrome using a reduced intensity conditioning regimen. Bone Marrow Transplant. May 26, 2008. 42(3):159-65.
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